• uncovered the fundamental mechanism of how human white cells kill foreign cells.
• helped demonstrate how "complement proteins" aid in killing.
• demonstrated how adriamycin, an anti-cancer drug, operates at the cellular level.
• conceived and developed the idea of splicing monoclonal antibodies to killing cells that seek out cancer cells, called directed effector cell killing.

Interest in Nutrition and Prevention
While thoroughly engrossed in basic science, Dr. Simone again found new direction as a result of direct contacts with cancer patients. One of his first patients was Vice President Hubert Humphrey who was dying of malnutrition secondary to his cancer. Later, a man his own age came to Simone at NCI and asked to be kept alive for the birth of his child. Intensive chemotherapy cleaned out the cancer, but he did not improve. "At last resort, I gave him high doses of vitamins and minerals that quickly produced a seemingly miraculous, but only temporary recovery." The man saw the birth of his son.

Newly interested in nutrition, Dr. Simone realized that existing cancer treatments produced limited results. Although billions are spent on research, the number of new cancer cases rise year after year. He decided to devote part of his time investigating the effects of nutrition on cancer and the possibilities of cancer prevention.

The result was a landmark book, Cancer and Nutrition, A Ten Point Plan to Reduce Your Chances of Getting Cancer (1982). This is the only book endorsed by George Stringfellow, a founder of the American Cancer Society. Dr. Simone now serves as a consultant to major corporations, foreign countries, and has been asked to advise prominent figures, including President Reagan, on the principles of cancer prevention.

Cancer and Heart Disease Prevention
"Most cancers and heart disease can be prevented since the majority are related to preventable factors: nutrition, tobacco, alcohol, etc. The first step is to change one's diet," Dr. Simone says, "to a low-fat, high-fiber diet, supplemented with certain vitamins and minerals. The incidence of cancer will decrease if people modify their risk factors."

KidStart Program for Children
Dr. Simone put his research to work in a program he calls "KidStart" based on their book, KidStart. "When children adopt a healthy lifestyle early in life, the incidence of cancer and cardiovascular disease will decrease significantly."

Integrative Medicine
Since 1981 Dr. Simone asserted that proper nutrition, supplements containing the proper doses, chemical form, and correct ratio of one nutrient to the other, and other lifestyle factors should be integrated with effective conventional therapies for patients, especially those undergoing radiation, chemotherapy, cardiac and other treatments. Dr. Simone was compelled to develop and manufacture these special nutritional formulae. Lifestyle modification improves health and outcome.

Breast and Prostate Health
The majority of his clinical practice since 1980 consists of patients with breast cancer, benign breast disease, and those who want to prevent both. Dr. Simone's comprehensive approach to obtain optimum breast health is shared in his book, The Truth About Breast Health and Breast Cancer, Prescription for Healing. And Dr. Simone explores his Plan for prostate health in his book, The Truth About Prostate Health and Prostate Cancer, Prevention and Cancer Life Extension.

Alternative Medicine
After he wrote Cancer and Nutrition in 1981, Dr. Simone was thrust into the alternative medicine arena. He searched the major rain forests for cancer treatments. He helped to shape the early days of the Office of Alternative Medicine (OAM), National Institutes of Health. At the request of the OAM, he pursued and received FDA approval to investigate the use of shark cartilage in advanced cancer patients. He also helped to organize Departments of Alternative Medicine for other Medical Colleges.

Sports Medicine
Because of his expertise in treating malnourished dehydrated patients who experience muscle wasting, he was asked to formulate a nutritional drink that can prevent dehydration and cramping. In 1990, the formula was tested and proven successful in the harsh conditions of the North African desert in Cairo, Egypt. Today, it is successfully used by World Class, Professional, and amateur athletes, as well as people in everyday activities.

Access to Supplements Ensured Health Care Fairness
Dr. Simone wrote the language that led to the compromise in the US Senate and finally the House ensuring that all Americans have free access to food supplements. He also conceived a health care reform plan that encourages fairness for all, recipients and employers.

Media
Dr. Simone has appeared on hundreds of television shows including 60 Minutes, Prime Time Live, etc; thousands of radio shows, and been written about in thousands of national and international print media. He is sought for medical and politically related issues.

Summary
Charles B. Simone, M.MS, M.D. is one of the few individuals in the world with formal training in medical oncology, radiation oncology and immunology, with expertise in nutrition, cancer prevention, and cancer detection. As one of the first physicians to champion integrative medicine, Dr Simone combines effective conventional and alternative modalities.

SIMONE PROTECTIVE CANCER INSTITUTE
The Simone Protective Cancer Institute [501 (C) 3 non-profit] was founded by Charles B. Simone, M.D. in 1980 for the purpose of carrying on scientific research, conducting public lectures, and educating people, especially children, concerning prevention, early detection, and treatment of diseases. Through research and education we expect to profoundly influence the way diseases are handled in America. Director Ida Billy Spritzer is helping to raise awareness and funds for our Children's Helping Hands for Hope. For a bold new attack on cancer, please make a tax deductible contribution to the Simone Protective Cancer Institute, 123 Franklin Corner Road, Lawrenceville, NJ 08648, 609-896-2646. Your contribution may be: Cash Gift, Bequests, Securities, Real Estate, Life Insurance, Art, Rare Books, Rare Coins, Rare Stamps.